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Word Count: 545
The genetic disorder I was told to research was the Sickle Cell Disease I will explain what mutation causes this disease the characteristics of it and what has developed in the area of gene therapy because of it The Sickle Cell Disease is an inherited disease The gene for hemogoblin-S which causes the disease is the most common inherited blood condition in America although most people only inherit one copy of the gene for HbS while the other gene hemogoblin-A is normal and can override HbS blocking the disease These people have the HbS trait but not the disease therefore leading a normal life For an offspring to acquire the disease both parents must have the HbS gene yet the child only has a 25 chance of having Sickle Cells You cannot catch the disease you are born with it and it is present for life There are many complications and harmful effects as the result of the Sickle Cell Disease The disease causes hemoglobin in the red blood cells when it does not receive sufficient oxygen to form into long sickle shapes with a sticky chemical surface When blood cells are this form they cannot go through the capillaries blocking off both blood and oxygen Fortunately only 20 of all red blood cells become Sickle Cells the sickle cells have a shorter life span and most blood cells go through the capillaries before becoming sickle-shaped The most painful effect known from Sickle Cell Disease are episodes of pain called Sickle Cell Crisis where the body is in need of oxygen either from physical activities or a sickle blood cell blocking blood passages that lead to organs The first day is the worst where devastating pain goes to the arm leg and back along with the shortness of breath The other symptoms of Sickle Cells include strokes increased infections early gallstones yellow discoloring of eyes and skin low blood cell counts anemia and delayed growth
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