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Nutritional Protocol For Inflammation When tissues are injured a specific reaction to the injury takes place A collection of irritants and other chemical mediators are released into the injured area to aid in stabilization of the injured tissue protection against further injury and stimulation of healing at the injury site These factors are referred to as the inflammatory cascade And it includes substances such as histamine bradykinin and prostaglandins which aid in vasodilation to the injured area serotonin which acts as a vasoconstrictor and growth factors and cytokines which act to increase fibroblast and macrophage migration to the injury site1 This is the acute inflammatory response and it is essential to the healing process It should be noted that this acute reaction is healthy and we do not want to impede this process We do however wish t aid the healing process in order to resolve the acute inflammatory response before it passes into a chronic state of inflammation It is th chronic state of inflammation that is always destructive to tissues and is equated to disease2 When repair is successful inflammation becomes a limited phenomena Some conditions such as asthma allergies autoimmune diseases fibromyalgia migraine headaches osteoarthritis peptic ulcers and psoriasis comprise examples of perpetual or chronic inflammation3 It is these chronic conditions hallmarked by pain and fatigue that eventually lead to loss of function The treatment that millions of people turn to each year is Non-Steroidal Anti-Inflammatory Drugs NSAIDs However long-term therapy has revealed an alarming list of adverse side effects associated with these drugs such as gastrointestinal bleeding and suppression of inherent anti-inflammatory pathways and tissue repair4 In addition NSAIDs have been linked to leaky gut syndrome in which gut permeability is increased allowing antigenic toxins to flood the systemic circulation via paracellular and transcellular absorption5 Thus nutritional modification is the best way to guard against adverse reactions or side effects More importantly nutritional status is the foundation in which inflammation
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