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I think a very good report Well doneyour best work yet Sickle Cell Anemia Sickle Cell Anemia is the most common hematologic hereditary disorder know toman It is a condition where the red blood cells RBC sometimes assume a strangesicklelike shape Observations date back to Herrick in 1910 but the molecularera for the study of Sickle Cell Anemia did not begin until the identification ofHemoglobin S Hb S by Linus Pauling in 1949 It is a worldhealth problempredominantly affecting Negroes in the Untied States and Africa and sometimesLatins 50 of those with Sickle Cell Anemia die before age 20 and most do notlive to reach age 40 Normal Red Blood Cells are shaped similar to donuts and pass easily throughthe blood stream to carry Oxygen to ALL parts of the body Sickle cells because ofthere odd shape do not easily pass through the blood vessels and tend to clog thembecause of this internal organs may not receive enough oxygen I in 10 AfricanAmericans carry the gene and about 1 in 400 AfricanAmericanchildren carry Sickle Cell Anemia If a person is hybrid for the disease they are said to have the sickle celltrait Their cells can be made to sickle in a test tube and under extremeconditions of exercise and at high altitudes This is rare and seldom seriousmost people with the trait live full normal lives The trait can never turn intothe anemia About 50 of the children of to parents who both have the trait will also havethe trait About 25 will be born with the anemia and about 25 will not beaffected by ether one o o T T TTrait AAnemia o o o o NNot Affected
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