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According to the FDA the steroid clobestasol propionate can cause stretch marks thinning skin and dilution of tiny blood vessels Large amounts or long term use can cause more serious side effects including hypertension central obesity diabetes hirsutism acne osteoporosis weakening of the bones impaired wound healing decreased resistance to infection muscular wasting and behavioral changes such as mania and psychosis The steroid can also suppress the bodys ability to produce its own corticosteroidsin helping it fight infection to deal with the body trauma Commonly used oral steroids include betamethasone Celestone Steroids hurt bones several ways They reduce amount of calcium through the kidneys This causes the body to release a parathyroid hormone to remove calcium from bones to restore the calcium level in the blood to normal Steroids also weaken the bone by simulating osteoclasts cells that break down bone and inhibitosteoblasts cells that build new bone As a result buildup of the bone cannot keep up with breakdown Within the first six months of cortisocrad therapy there can be a 10 to 20 percent loss of bone mass One in four could suffer a fracture as a result Transplant patients take steroids to prevent rejection of donor tissue Steroids are also for shorter periods to treat acute inflammation and severe allergic reactions The drugs can be taken by mouth injection or inhalation or they can be incorporated into drops or a lotion or cream They typically impair bone health ony when taken orally or by injection on a regular basis Recent studies have shown that chronic uses of doses as low as 75 milligrams a day can cause gradual bone loss The idealized male body image nowadays is beefy and muscled McClelland 1 The FDA also warned that ceasing use of Skin-Cap without a dermatologists help could worsen psoriasis or even convert plaque psoriasis to pustular psoriasis An early red flag raised in June
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