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Neuromuscular blocking agents are an essential aspect of attaining adequate muscle relaxation in patients prior to attempting endotracheal intubation Succinylcholine is one these agents used most commonly when attempting a rapid sequence induction Succinylcholine administration is associated with muscle fasciculations and subsequent myalgias postoperatively A nondepolarizing neuromuscular agent is commonly administered to reduce the occurance of fasciculations and myalgias Additionally the induction agent Propofol has been associated with further reducing fasciculations and myalgias Propofol and Pentothol are commonly used anesthetic agents and are generally interchangable and equally efficacous Studies have elluded to the ability of Propofol to reduce theses occurances but it has not been demonstrated in all areas This study hypothesis that when a standard dose of nondepolarizing agent is given in conjuction with Propofol the occurances of fasciculations and myalgias will be reduced more effectively than with PentotholAn all male population has been selected to reduce confounding results that may be attained when female subjects are studied as females are generally accepted to have greater levels of postoperative myalgia Routine induction will proceed with the patient receiving standard doses of Fentanyl Versed and a defasciculating dose of Rocuronium calculated at 10 of the induction dose Group A will receive 15 mgkg to 2 mgkg of Propofol and Group B will receive 3 mgkg to 5 mgkg of Pentothol Patients will be graded on occurances of fasciculations on a scale of 0 none to 3 severe Patients will be contacted at 24 hours postop to ascertain a self report of perceived muscle myalgia and will be reported on a scale of 0 none to 10 severeThe results of this study will be expected to demonstrate that the administration of Propofol will significantly reduce the incidence of fasciculations and myalgia over the adminstration of Pentothol Conculusions should demonstrate that administrating Propofol when attempting a rapid sequence induction with Succinylcholine will decrease patients fasciculations and perception of postoperative myalgiasNeuromuscular blocking agents are an essential aspect of
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