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Campaign for RU486 Contraceptive ResearchPicture Feminist Majority Foundation The Medical Uses of Mifepristone In addition to its use in terminating unwanted pregnancies MIFEPRISTONE formerly known as RU-486 also may be effective in treating a range of serious diseases and medical conditions many of which particularly affect women Yet American clinical trials for most of these uses have come to a standstill due to anti-abortion politics A B O R T I O N F E R T I L I T Y C O N T R O L Available to women in many countries but currently not in the US mifepristone formerly known as RU-486 is the first in a new generation of fertility control agents that can terminate an early pregnancy Mifepristone works by blocking the action of progesterone which is necessary to sustain a pregnancy Mifepristone taken along with a prostaglandin has been used by over half a million women worldwide and has found to be safe and effective as an early abortion method during the first nine weeks of a pregnancy A woman can take mifepristone as soon as she knows she is pregnant Mifepristone is administered orally is non-invasive requires no anesthesia and bears less risk of infection Many women prefer mifepristone because the procedure is more private and allows them greater psychological control in ending a pregnancy Administered with a single dose of a misoprostol a prostaglandin given as orally or as a vaginal suppository mifepristone has been proven to be highly effective in successfully terminating pregnancy1 Studies also show that mifepristone is a safe effective post-coital contraceptive2 3 Preliminary shows show as well that mifepristone can act as both a male and female contraceptive 1 Spitz IM et al Early pregnancy termination with mifepristone and misoprostol in the United States New England J of Medicine 43098 2 Baird DT Dewar M Glasier A et al Mifepristone RU486 compared with high-dose
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