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The Dawn of a New Age April 1956 The pharmaceutical company Parke Davis first synthesize what they believe to be the perfect anesthetic Souza 1995 When administered to patients it causes a completely dissociative state with no significant respiratory or cardiovascular depression Patients appear to be awake eyes open breathing normallybut are unaware of their surroundings or the procedures being performed upon them Souza 1995 Indeed this is the perfect drug Unfortunately like all good things this one has a darker side 15 of patients awake from their slumber with what appeared to be an acute case of paranoid schizophrenia Peterson Stillman 1978 The drug is PCP and to this day it is the scourge of the underground drug community and the focal point of intense scientific research Parke Davis and Company did not know how terrible and wonderful a discovery they made that day but our world has been changed forever because of itquite possibly for the better The Dust of Angels Phencyclidine more commonly known as PCP is a polycyclic compound belonging to the arylcyclohexylamine class of chemicals figure 10 Souza 1993 In pure form it is a white powder which readily dissolves in water The cyclohexamines are known for their the potent neurological effects with PCP being the most potent Almost every variation has been administered to or abused by humans at some time Nintey Fifth Congress 1978 All these compounds have similar pharmacological effects which vary considerably according to the amount administered Small doses produce a drunken state in which subjects report a numbness in the extremities while some species like dogs and cats become quite excited Halberstadt 1995 Intermediate doses have anesthetic and analgesic effects with the psychic state resembling sensory isolation with one important exception the sensory impulses when tested electrophysiologically reach the neocortex but the neuronal signals are grossly distorted Halberstadt 1995 Large doses especially of PCP may produce convulsions
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