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A study conducted by Dykman and Tone 1998 took 50 subjects with a physicians diagnosis of fibromyalgia FM and or Chronic Fatigue Syndrome CFS and interviewed them with a structured interview form Nine months later a follow up interviews was completed In addition all subjects in the study had previously received some form of medical treatment massage therapy biofeedback physical therapy etc before taking the nutritional supplements but with no lasting success CFS has been thought of as a variant of the more serious FM CFS and FM share these same symptoms recurrent low grade fever swollen glands sore throat forgetfulness confusion inability to think concentrate depression and irritability Additional symptoms of FM not found in CFS are chronic and or acute pain in neck shoulders and back and hip morning stiffness and aching hypersensitivity to cold heat abdominal pain constipation diarrhea headaches swelling in the hands and feet anxiety and or depression and lack of restful sleep sleep disturbance disorders Dykman Tone 1998 FM is characterized by greater muscle and fibrous tissue pain and CFS by greater fatigue and depression Although both conditions lack any cure CFS is more apt to improve with time and treatment when compared to FM Dykman Tone 1998 This study used 48 females and 2 males with a physicians diagnosis of FM and or CFS that were drawn from a national nutritional meeting 25 had FM diagnosis 12 CFS diagnosis and 13 had both diagnoses Ninety- seven percent were Caucasian Every subject was interviewed by a health care professional Previously every subject had tried at least one traditional therapeutic method However before the first interview all 50 subjects had been taking nutritional supplements for at least one month Subjects were asked to self-rank their own symptoms on a 21-symptom questionnaire of CFS and FM using a four-point scale 1 mild to 4 debilitating The average ranking before taking nutritional supplements was 35
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