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cures await discovery Although the list is pretty much endless here are some examples by decade including the main species used that were crucial to the discovery Pre-1900 Treatment for rabies dogs rabbits smallpox cows anthrax sheep 1900s Cardiac catheterization techniques dogs rabbits treatment for rickets dogs 1920s Discovery of insulin dogs 1930s Development of modern anesthesia dogs prevention of tetanus horses development of anticoagulants cats 1940s Treatment of rheumatoid arthritis rabbits monkeys discovery of the RH factor monkeys prevention of diptheria horses antibiotics rats mice rabbits etc treatment for whooping cough pigs and rabbits 1950s Prevention of polio rabbits monkeys rodents discovery of DNA rats and mice development of open-heart surgery and pacemaker dogs development of cancer chemotherapy monkeys rabbits and rodents 1960s Development of lithium treatment rats and guinea pigs prevention of rubella monkeys 1970s Prevention of measles monkeys treatment for leprosy monkeys armadillos heart bypass surgery dogs 1980s Development of monoclonal antibodies for treating diseases mice rabbits organ transplant advances dogs sheep cows and pigs 1990s Laproscopic surgical techniques pigs breast cancer genetic and environmental links fruit flies mice and rats gene therapy for cystic fibrosis mice and primates It is often hard to conceptualize the impact of a disease once a vaccine has been developed and it is no longer a threat Likewise it is often difficult for young and healthy people who arent exposed to as much risk and who accordingly havent had the misfortune to experience a life-threatening or painful disease to see that the use of animals in research was and is crucial to ensuring their health and others health Even before a vaccination against a disease is developed what can be learned through research using animals about the nature of transmission and specific susceptibility factors associated with the disease can help reduce or prevent exposure One specific example is the Hepatitis B virus HBV which infects about 240000 people each year in the United States This infection
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