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Major depressive disorder sometimes referred to as Unipolar Depression describes a leading disruptive mental state which effects about 10-20 percent of the worlds population in the course of a lifetime This disorder must be regarded as a significantly important state as it strikes its victim psychologically socially and sometimes even physically impairing normal daily behaviour Understanding Major Depressive Disorder HISTORY Out of the many mental illnesses that have either arose or been discovered depression has the longest background in history Societies and cultures throughout the ages have noticed depression classifying it as an illness as a symptom to a disease as insanity unaware as to why the despondency and mournfulness had come about or what to do to alleviate this state from its victim The first obvious and direct reference to depression or major depressive disorder as it is now referred to was conveyed by Hippocrates in 400 BC who labeled this disorder melancholia This term was later referenced to in about 30 AD by Aulus Cornelius Celsus Aulus Cornelius Celsus wrote in his monumental 15th century encyclopedia De medicina which is now regarded as one of the greatest medical classics though it was predominantly disregarded by his contemporaries about his belief that melancholia was caused by a physical affliction of black bile Later in the 12th Century Moses Maimonides a redoubtable Jewish philosopher jurist and physician claimed that melancholia was in fact a singular disease not a symptom side effect or mystical occurrence As scientific methods and theories developed over time the concept of depression though it lost its classification as melancholia remained one of controversy with different arguments as to its cause and cure and surely will continue to be debated upon for centuries to come EPIDEMIOLOGY Major depressive disorder is a common disorder paining both women and men though depression is more frequent in women than in men with a striking lifetime prevalence of approximately 15 percent In fact
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