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KLINEFELTER SYNDROME THE XXY BOY IN THE CLASSROOM Although there are exceptions XXY boys are usually well behaved in the classroom Most are shy quiet and eager to please the teacher But when faced with material they find difficult they tend to withdraw into quiet daydreaming Teachers sometimes fail to realize they have a language problem and dismiss them as lazy saying they could do the work if they would only try Many become so quiet that teachers forget theyre even in the room As a result they fall farther and farther behind and eventually may be held back a grade CAUSES No one knows what puts a couple at risk for conceiving an XXY child Advanced maternal age increases the risk for the XXY chromosome count but only slightly Furthermore recent studies conducted by NICHD grantee Terry Hassold a geneticist at Case Western Reserve University in Cleveland OH show that half the time the extra chromosome comes from the father Dr Hassold explained that cells destined to become sperm or eggs undergo a process known as meiosis In this process the 46 chromosomes in the cell separate ultimately producing two new cells having 23 chromosomes each Before meiosis is completed however chromosomes pair with their corresponding chromosomes and exchange bits of genetic material In women X chromosomes pair in men the X and Y chromosome pair After the exchange the chromosomes separate and meiosis continues In some cases the Xs or the X chromosome and Y chromosome fail to pair and fail to exchange genetic material Occasionally this results in their moving independently to the same cell producing either an egg with two Xs or a sperm having both an X and a Y chromosome When a sperm having both an X and a Y chromosome fertilizes an egg having a single X chromosome or a normal Y- bearing sperm fertilizes an egg having two X chromosomes an XXY male is
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