scroll to top
Stuck on your essay?
Get ideas from this essay and see how your work stacks up
Word Count: 1,198
The medications most frequently prescribed for uncomplicated depressive illness are the selective serotonin reuptake inhibitors or SSRIs These medications increase levels of serotonin in synapses in the brain by reducing the ability of the presynaptic nerve cell to reabsorb the neurotransmitter after it is released As far as the postsynaptic nerve cell can tell the presynaptic cell is releasing more serotonin Research into serotonin has taken center stage in the 1990s due to the therapeutic success of Prozac and related antidepressants that manipulate serotonin level Serotonin levels at the synaptic cleft of depressed patients are low In addition levels of a surface molecule unique to serotonin-releasing cells in the brain are lower in depressed patients than in healthy subjects Studies have also shown that the density of at least one form of serotonin receptor is greater in postmortem brain tissue of depressed patients This greater up-regulation is a suggestion of a compensatory response to too little serotonin in the synaptic cleft SSRIs work by blocking the reuptake of serotonin therefore allowing a higher serotonin concentration at the synaptic cleft SSRIs are increasingly prescribed because they are effective and have fewer side effects than the older tricyclic antidepressants In addition to being prescribed as an antidepressant SSRIs are helpful in treating panic disorder obsessive-compulsive disorder OCD eating disorders social phobia and possibly post-traumatic stress disorder PTSD A good response to SSRIs is seen in 70 or so of uncomplicated major depression as compared with a 30 placebo rate A similar success rate is seen in treating panic attacks but they are less effective than the minor tranquilizers in reducing generalized anxiety In OCD it is common to see a 50 reduction in symptoms Given the various symptoms SSRIs can treat clinicians view them as a broad-spectrum psychiatric medication SSRIs usually do not work immediately but require two to four weeks for the full therapeutic effect to develop This can be frustrating for the patient because
@Kibin is a lifesaver for my essay right now!!
- Sandra Slivka, student @ UC Berkeley
Wow, this is the best essay help I've ever received!
- Camvu Pham, student @ U of M
If I'd known about @Kibin in college, I would have gotten much more sleep
- Jen Soust, alumni @ UCLA