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Modern wound management is a challenging and rewarding area of clinical practice for the student nurse This modern approach involves simple advances in practice Firstly modern wound management uses moist wound healing processes that have been researched and determined to be significantly more effective than the dry healing of the past Secondly and more importantly it is a more holistic approach that looks at more than the wound itself but addresses the whole patient in medical environmental and social contexts Waldrop Doughty 2000 Most sources indicate that wound healing is made up of an orderly sequence of events This in turn is characterised by specific movement of specialised cells into the wound carrying out specific tasks Bale Harding Leaper 2000 According to the movement of the cells and the orderly sequence of events in healing is regulated by cytokines or growth factors The healing stage of photo 3 appears to be the Proliferative or regeneration stage Evidenced by its colour - bright red moist and shiny appearance As a student nurse it would always be well off to remember that healing is a continuum of complex connected processes that are divided into phases These phases are known as the inflammatory phase the proliferative phase the maturation phase This essay will list the series the events that occur during the granulation epithelisation and contraction stages of the proliferative phase Granulation Also known as Angiogenesis which is the growth of new blood vessels Bale et al 2000 Is an essential ingredient for regeneration of granulation tissue Tissue hypoxia low oxygen sets in following disruption to the blood flow on injury stimulating macrophages to secrete a substance known as angiogenesis factor The process of angiogenesis is delayed if a thick layer of surface necrosis is present Waldrop et al 2000 According to Hopkinson 1992 undamaged capillaries beneath the wound produce buds stimulated by growth factors these buds form a network of loops which fuse with other
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