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Word Count: 971
In the human body each cell contains 23 pairs of chromosomes one of each pair inherited through the egg from the mother and the other from the sperm of the father Of these chromosomes those that determine sex are X and Y Females have XX and males have XY In addition to information concerning sex the X chromosomes carry determinants for a number of other features of the body including the levels of factor Vlll and lX If the genetic information determining factors Vlll and lX is defective hemophilia results As a result the protein factors needed for normal blood clotting are effected In males the single X chromosome can not compensate for the lack and will show the defect In females however only one of the two chromosomes will be abnormal In very rare cases however she will have inherited two defective X chromosomes and herself will be a hemophiliac If she is not affected and the gene is recessive she is now classified as a carrier In some cases there is no previous record of hemophilia in the family Male children who would be born with hemophilia would be the result of the mutation of the gene There are two types of hemophilia Hemophilia A and Hemophilia B Hemophilia A also known as Classical Hemophilia is caused by a factor Vlll deficiency This is the most common form of hemophilia The second type of hemophilia is Hemophilia B and is sometimes referred to as the Christmas Disease Hemophilia B is caused by a factor lX deficiency Both types of hemophilia are characterized by prolonged episodes of bleeding especially into joints muscles internal organs or even brain hemorrhaging Hemophiliacs do not bleed harder of faster than a normal unaffected person Instead they suffer from prolonged bleeding The reason a hemophiliac will suffer from prolonged bleeding is the inability of the blood to form clots This is the result of the missing reduced clotting
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