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Tyler McKinna Juvenile Rheumatoid Arthritis Alternative Names Juvenile chronic polyarthritis JRA Still disease Definition A chronic inflammatory disease that may cause joint or connective tissue damage The onset occurs before Age 16 Causes incidence and risk factors JRA is thought to belong to the collagen classes of disease those diseases that involve connective tissue It is a complicated disease The primary manifestation is arthritis but the disease may involve other body systems such as the heart and lining around the heart pericardium lungs and lining around the lungs pleura eyes and skin Systemic arthritis affects 20 of those with juvenile arthritis and includes fever rash and enlarged spleen splenomegaly in addition to joint inflammation JRA is generally divided into five broad groups depending on whether a large number of joints are involved or just a few whether the rheumatoid factor a blood test is positive or negative and whether there is eye involvement or not The five categories of JRA may be roughly broken down as follows many involved joints and a positive rheumatoid factor many involved joints and a negative rheumatoid factor few involved joints and a positive antinuclear antibody few involved joints and a positive HLA B27 surface antigen systemic JRA throughout the body A specialist in rheumatology generally makes the category determination The onset of arthritis may be slow or extremely rapid An early sign of slow onset may be stiffness on arising in the morning Swollen painful joints characterize the arthritis of JRA with pain on motion and sometimes to touch The skin over the joints is generally not red but can be The systemic form of JRA may first appear with high fevers chills and a rash but without joint pain In the systemic form arthritis may develop months after the appearance of the
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